Abstract #3681

Evaluation of Accuracy of MR phase and R2* for susceptibility quantification

Yongquan Ye¹, Li Yang², Mengsu Zeng², Shengxiang Rao², Ying Ding², Jinguang Zong³, and Xixi Wen³

¹United Imaging of Healthcare America, Houston, TX, United States, ²Department of Radiology, Shanghai Institute of Medical Imaging, Zhongshan Hospital, Fundan University, Shanghai, People's Republic of China, ³Shanghai United Imaging of Healthcare, Shanghai, People's Republic of China

Computer simulation was performed to evaluate the relationship between a voxel's bulk susceptibility and its R₂* or phase behavior. A virtual voxel with multi-dipole model was created, and the effects of dipole properties on the accuracy and consistency of R₂* and phase on reflecting the voxel’s bulk susceptibility was investigated. Linearity is only observed at low bulk susceptibility regime, and phase is much more robust against various susceptibility dipole properties than R₂*.

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