To reduce the calculation error and artifacts of susceptibility in the boundary region between water and fat, a new reconstruction method is presented and applied to a prostate QSM. In the proposed method, susceptibility maps of the water region and the fat region are calculated separately and differently and then combined. Numerical simulation and human prostate imaging using a 3T-MRI are performed to evaluate accuracy and artifacts of the proposed method. The results suggest that the proposed method reduces calculation error and the shading artifacts in the boundary region between water and fat near the prostate.
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