The focus of the presented work is to understand the relation between electrical conductivity and tissue composition in terms of 23Na concentration and water fraction. This would be relevant to evaluate the potential value of electrical conductivity imaging as a new endogenous biomarker and the validity of accessing conductivity from water content. For this purpose, MR-EPT and waterEPT conductivity reconstructions are performed and compared to network analyzer measurements. To evaluate whether conductivity is directly related to the total sodium concentration in free water, 23Na images are acquired at 7T and conductivity reconstruction are then performed using the Stogryn’s model.
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