Abstract #3434

Characterization of brown and white adipose tissue in 7-year old children

Jonathan Andersson¹, Emma Kjellberg^2,3, Elin Lundström¹, Mathias Engström⁴, Josefine Roswall^2,3, Stefan Bergman⁵, Pär-Arne Svensson⁶, Håkan Ahlström^1,7, Jovanna Dahlgren², and Joel Kullberg^1,7

¹Department of Radiology, Institution of Surgical Sciences, Uppsala University, Uppsala, Sweden, ²Department of Pediatrics, the Institution of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ³Department of Pediatrics, Halland Hospital, Halmstad, Sweden, ⁴Applied Science Laboratory, GE Healthcare, Uppsala, Sweden, ⁵Primary Health Care Unit, Department of Public Health and Community Medicine, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ⁶Department of Pediatric Radiology, The Sahlgrenska University Hospital, Gothenburg, Sweden, ⁷Antaros Medical, Mölndal, Sweden

The purpose of this study was to characterize and compare brown and white adipose tissue in 7 year-old overweight/obese and normal weight children using whole-body water-fat MRI. Correlations were also performed between the brown adipose tissue measurements and other measurements, such as VAT and SAT volumes. Results overall showed expected differences and associations to several measures relevant for obesity. We conclude that whole-body water-fat MRI of 7 year-old children is feasible and allows characterization of brown and white adipose tissue.

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