This study explored the relationship between restriction spectrum imaging (RSI) and diffusion kurtosis imaging. Regions of interest for suspicious lesions and background tissue were identified in four patients with PIRADS 5 lesions. Kurtosis was estimated using either the signal fractions obtained from the RSI fit or the cumulant expansion for the NMR diffusion signal. A strong relationship was observed between RSI-derived restricted signal fraction and RSI-derived kurtosis. The performance of these two metrics was comparable in discriminating between suspicious lesions and background prostate tissue, and both outperformed the cumulant expansion approximation to kurtosis.
This abstract and the presentation materials are available to members only; a login is required.