This retrospective study was to determine the diagnostic accuracy of apparent diffusion coefficient (ADC) values to assess the response to CRT in patient with local advanced rectal cancer by using histogram analysis derived from single-section (SS) and whole-tumor volume (WTV) regions of interest (ROIs). and found that Post-CRT ADC histogram metrics yield greater accuracy in discrimination between good and poor responders, especially in improving the specificity, compared with the mean ADC values.
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