In this work, primary tumors of the central nervous system, including glioma and meningiomas, were studied with NODDDI. The parameters derived from NODDI was examined to differentiate peritumoral edema and characterize complex structural abnormalities using diffusion MRI (dMRI) of a clinical MRI scanners. As a result, a better understanding of this perplexity with the aid of modern imaging is clearly necessary to define the blurred tumor margins and confront the recurrences in long-term treatment.
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