The powder-averaged signal is used in several analysis techniques in diffusion MRI. Assuming uniformly distributed diffusion encoding directions, it is calculated simply as the arithmetic signal average. However, perfectly uniform sampling is generally unattainable.
We demonstrate how non-uniformity can be accounted for by using weighted signal averaging, and we describe how optimal weights can be calculated for existing diffusion encoding schemes to yield improved accuracy of the powder average estimate.
This abstract and the presentation materials are available to members only; a login is required.