Abstract #3217

Interobserver reproducibility of blood flow measurements with an abdominal 4D flow MRI sequence with spiral sampling and compressed sensing

Octavia Bane¹, Steven Peti², Mathilde Wagner^1,3, Stefanie Hectors¹, Hadrien A Dyvorne^1,4, and Bachir Taouli^1,2

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Radiology, Groupe Hospitalier Pitié Salpêtrière, Paris, France, ⁴4Catalyzer, Guilford, CT, United States

Our study evaluated the interobserver reproducibility of flow quantification in abdominal vessels using a novel 4D flow phase-contrast (PC) MRI sequence. The effect of liver fibrosis on blood flow metrics was also examined in 20 patients. Time-averaged vessel cross-section area, through-plane velocity and volume flow measured in 14 abdominal vessels in a subset of 10 patients were found to have acceptable interobserver agreement (Cohen’s kappa 0.762). A significant increase in the hepatic artery velocity and flow, splenic vein area and flow, middle hepatic vein velocity and flow, and right hepatic vein velocity was observed in patients with advanced fibrosis/cirrhosis.

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