Abstract #3212

Fast self-gated 4D flow measurements in the murine aortic arch with retrospective radial sampling

Patrick Winter¹, Kristina Andelovic², Thomas Kampf^1,3, Peter Jakob^1,4, Wolfgang Bauer², and Volker Herold¹

¹Experimentelle Physik V, Universität Würzburg, Würzburg, Germany, ²Medizinische Klinik und Poliklinik I des Universitätsklinikums Würzburg, Würzburg, Germany, ³Universitätsklinikum Würzburg, Institut für Diagnostische und Interventionelle Radiologie, Würzburg, Germany, ⁴Fraunhofer IIS, Fraunhofer EZRT, Magnetresonanz- und Röntgenbildgebung (MRB), Universität Würzburg, Würzburg, Germany

A self-navigated radial 4D-PC sequence is presented for accelerated ECG-free 4D flow measurements in the murine aortic arch. Self-navigation signals were extracted from the radial DC signal and used for retrospective motion synchronization. 3D-Cines with 30 frames were reconstructed with a spatial resolution of 100 µm. The volume flow was determined at 4 2D slices extracted from the 3D dataset and the 3D flow was visualized with streamlines. The results are in good accordance with results reported for ECG-triggered measurements. The new method yields high potential for preclinical studies of hemodynamics and can also be transferred to applications in humans.

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