Abstract #3169

Intravoxel Incoherent Motion Analysis for Perfusion Using Portal Vein Embolization Pig Model

Jia Ning¹, Tilman Schubert^2,3, Huijun Chen¹, Chun Yuan^1,4, and Scott B Reeder^3,5,6,7,8

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People's Republic of China, ²Clinic for Radiology and Nuclear Medicine, Basel University Hospital, Basel, Switzerland, ³Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Radiology, University of Washington, Seattle, WA, United States, ⁵Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁷Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁸Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Portal vein embolization (PVE) is often performed before liver tumor resection, to induce hypertrophy of the anticipated liver remnant and reduce the complications after partial liver resection. The perfusion changes of the embolized and non-embolized liver segments are of great interest. Intravoxel incoherent motion (IVIM) is a component of the diffusion weighted signal model that allows for separating estimation of perfusion. Estimation of IVIM from diffusion weighted imaging which may provide a unique way to measure the perfusion of liver tissue. This study aimed to test the intra-observer repeatability of IVIM and parameters change after PVE used a pig model.

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