Fluorinated amino acids are of high interest in biochemistry and pharmaceutics. The low 19F MR signal was increased employing hyperpolarization (photo-Chemical Induced Dynamic Nuclear Polarization, photo-CIDNP). 3-Fluoro-tyrosine in physiologic salt solution was hyperpolarized in presence of an albumin derivative using a low cost LED allowing repetitive irradiation and increasing the hyperpolarized signal. A clear 19F signal enhancement could be observed. In comparison to past examinations with a laser system, only small temperature changes caused by LED light irradiation were measured in the current study.
This abstract and the presentation materials are available to members only; a login is required.