Abstract #2981

7 Tesla 1H MR Spectroscopy of the Motor Cortex following Transcranial Direct Current Stimulation

Kayla Ryan^1,2, Krzysztof Wawrzyn³, Joseph Gati¹, Blaine Chronik^1,2,3, Neil Duggal⁴, and Robert Bartha^1,2

¹Centre for Functional and Metabolic Mapping, Robarts Research Institute, London, ON, Canada, ²Medical Biophysics, Western University, London, ON, Canada, ³Physics and Astronomy, Western University, London, ON, Canada, ⁴Clinical Neurological Sciences, Division of Neurosurgery, London Health Sciences Centre, London, ON, Canada

Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that has been used to treat numerous cognitive and motor disorders. However, its mechanism of action is poorly understood, resulting in controversy over its effectiveness. The current study used ultra-high magnetic field (7 Tesla) magnetic resonance spectroscopy to determine if metabolite ratios were altered after the application of tDCS. In this preliminary study of 8 subjects, we found no differences in metabolite ratios in the motor cortex immediately following stimulation.

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