Abstract #2957

3D Multi-Echo Radial Imaging of $$$^{23}$$$Na (3D-MERINA) for time-efficient multi-parameter mapping

Yasmin Blunck¹, Sonal Josan², Brad A Moffat³, Roger J Ordidge³, Jon O Cleary^3,4, and Leigh A Johnston^1,4

¹Electrical & Electronic Engineering, University of Melbourne, Melbourne, Australia, ²Siemens Healthcare, Melbourne, Australia, ³Anatomy & Neuroscience, University of Melbourne, Melbourne, Australia, ⁴joint senior authors

Challenging imaging characteristics (low SNR, fast bi-exponential decay) have so far limited the application of ²³Na-MRI in clinical environments. This work presents 3D Multi-Echo Radial Imaging of ²³NA (3D-MERINA), a time-efficient acquisition protocol from which multiple parameter maps (sodium-density, T₂*_slow and T₂*_fast, free ²³NA) can be derived in a single acquisition. Phantom and in-vivo measurements were analysed for the evaluation of parameter mapping and the inference of tissue characteristic based on decay behaviour. All parameters were acquired in a single sodium-density-weighted acquisition under relatively low SAR. Future investigation will exploit 3D-MERINA for SQF-SNR enhancement and the detection of MQF contrasts.

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