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Abstract #2859

Quantification of blood flow in the great veins and right heart using 4D flow MRI in Chronic Obstructive Pulmonary Disease: A pilot study in the MESA COPD Study

Ozair Rahman1, Carmen Blanken2, Pallavi P Balte3, Bharath Ambale Venkatesh4, Martin Prince5, David A Bluemke6, Oliver Wieben7, Joao Lima8, Stephen M Dashnaw9, James Carr2, Graham G Barr3, and Michael Markl2

1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Radiology, Northwestern University, Chicago, IL, United States, 3Epidemiology, Columbia University, New York, NY, United States, 4John's Hopkins, Baltimore, MD, United States, 5Radiology, Cornell, New York, NY, United States, 6Radiology and Imaging Sciences, National Institutes of Health, Bathesda, MD, United States, 7Radiology, University of Wisconson-Madison, Madison, WI, United States, 8Radiology, John's Hopkins, Baltimore, MD, United States, 9Radiology, Columbia University, New York, NY, United States

Chronic Obstructive Pulmonary Disease is the third leading cause of death in the United States, and affects 24 million Americans with over 65 million people affected world-wide. Up-to 58% of patients develop exertional pulmonary hypertension and right ventricular volume changes. Understanding this phenomenon, known as cor pulmonale can help us gain insight into the complex pathophysiology involved. This pilot study attempts to apply 4D flow MRI in patients with varying degrees of COPD, and assess the feasibility, reproducibility and accuracy of this technique.

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