USPIO-based, functionalized contrast agents targeting VCAM-1 enable the visualization of inflamed areas in the vessel wall during early atherogenesis. We present a novel 3D technique for coverage of the whole aortic arch at high spatial resolution and a time-resolved detection of nanoparticles with an ECG-free flow-compensated radial 3D-Cine acquisition. T2* weighted 3D-Cines were acquired using two different gradient echoes to provide phase difference maps. The results indicate a reliable detection of the nanoparticles with the new method due to a true 3D coverage of the aorta and the additional phase information.
This abstract and the presentation materials are available to members only; a login is required.