Abstract #2593

Accumulated Thermal Dose in MR-Guided Focused Ultrasound for the Treatment of Essential Tremor

Yuexi Huang¹, Nir Lipsman², Michael L. Schwartz², Vibhor Krishna³, Francesco Sammartino³, Andres Lozano³, and Kullervo Hynynen^1,4

¹Sunnybrook Research Institute, Toronto, ON, Canada, ²Division of Neurosurgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada, ³Division of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada, ⁴Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada

In focused ultrasound treatment of essential tremor, MR temperature and thermal dose measurements were crucial in guiding acoustic parameters. In this study, accumulated thermal doses from repeated sonications were integrated after chemical-shift artifacts were corrected retrospectively. Accumulated thermal dose measurements showed good correlation to lesion size in followup MR imaging.

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