This study reports the preliminary application of high-resolution diffusion tensor imaging (DTI) using readout segmentation of long variable echo trains (RESOLVE) sequence for spinal cord imaging in patients with demyelinating conditions. Patients with clinical isolated syndrome (CIS) and multiple sclerosis (MS) were recruited in order to investigate image evidences in early stages and the progression of the disease. The results of DTI analyses demonstrate that MS is characterized by diffuse axonal compensation in the spinal cord.
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