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Abstract #2515

Mathematical Modeling for Evaluating Gustatory Stimulation of Parotid Gland by Proton Density MRI

Yu-Chia Cheng1, Yi-Jui Liu2, Yi-Hsiung Lee3,4, Hing-Chiu Chang5, Hui-Chu Chiu6, Ta-Wei Chiu7, Kang Hsu8, Hsian-He Hsu4,9, and Chun-Jung Juan4,9

1Master 's Program of Biomedical Informatics and Biomedical Engineering of Feng Chia University, Taichung, Taiwan, Taichung, Taiwan, 2Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Republic of China, 3Ph.D. program in Electrical and Communication Engineering in Feng Chia University, Taichung, Taiwan, Republic of China, 4Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China, 5Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, 6Ph.D. program of Technology Management, Chung Hua University, Hsinchu, Taiwan, Republic of China, 7Department of Medicine, Taipei Medical University, Taipei, Taiwan, Republic of China, 8Department of Dentistry, National Defense Medical Center, Taipei, Taiwan, Republic of China, 9Department of Radiology, National Defense Medical Center, Taipei, Taiwan, Republic of China

The parotid gland function is evaluated by gustatory stimulation using scintigraphy in clinic. Due to the saliva secretion of parotid, it is supposed to measure the water component of parotid gland using PD MRI instead of scintigraphy. Normally the drop magnitude and recover rate of signal-time curve after gustatory stimulation was used to evaluate the function of parotid gland. For more physiology and quantitative parameters of characteristics of signal-time curve, we developed a mathematical model for drainage and refill of a toilet tank to quantify the parotid gland function in this study.

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