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Abstract #2466

PC-MRI OF CEREBRAL BLOOD AND CSF FLOW VERSUS INTRACRANIAL PRESSURE MONITORING IN HYDROCEPHALUS PATIENTS

Armelle Lokossou1, Olivier Baledent1, Simon Garnotel1, Gwenaël Pagé1, Laurent Balardy2, Zofia Czosnyka3, Pierre Payoux4, and Eric A. Schmidt5,6

1Departments of Medical Image Processing, BioFlowImage Laboratory, University Hospital of Picardie Jules Verne, AMIENS, France, 2Department of Internal Medicine and Gerontology, Toulouse University Hospital, Toulouse, France, 3Neurosurgical Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., 4Department of Nuclear Medicine, CHU Toulouse, Purpan University Hospital, Toulouse, France, 5UMR 1214 – INSERM/UPS – TONIC Toulouse Neuro-Imaging Center, Toulouse, France, 6Departments of Neurosurgery, University Hospital of Toulouse, France

The neurosurgical guidelines recommend low invasive intracranial pressure (ICP) monitoring with infusion tests to detect CSF dynamics alteration. In this study, we investigate how PC-MRI could be helpful in intracranial flow investigations. Eighty-three patients suspected of active hydrocephalus underwent the conventional ICP investigations. All the patients had also the day before, a rapid and simple PC-MRI to assess their cerebral blood and CSF flows. We found that patients who presented altered CSF dynamics (observed by ICP monitoring) presented also the smallest cervical CSF oscillations in the population. PC-MRI brings easy, quick and non-invasive complementary information to investigate the craniospinal dynamic.

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