Multiple post labeling delay arterial spin labeling provide dynamic perfusion information in patients with intracranial artery atherosclerostic stenosis, and is of useful to study collatera circulation. In this study, two PLD ASL was used to evaluate the severity of hypoperfusion in patients with unilateral middle cerebral artery (MCA) stenosis and we found that the severity of hypoperfusion assessed by two PLD ASL was significantly correlated with collateral circulation and associated with recurrent ischemic stroke in these patients.
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