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Abstract #2288

Assessing white matter tract development in formula fed versus breastfed infants at 1 month and 3 months

Giang-Chau Ngo1,2, Clarisa Carruthers3, Catherine Vu3, Alex Cerjanic1,2, Monica Muthaiya1, Marie Drottar3, Jonathan Litt4, Ivan Frantz4, Ryan Larsen2, Borjan Gagoski3, P. Ellen Grant3, and Bradley P. Sutton1,2

1Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3Boston Children’s Hospital, Boston, MA, United States, 4Beth Israel Deaconness, Boston, MA, United States

Diffusion Tensor Imaging and Tract-Based Spatial Statistic on FA, RD and AD were applied to investigate white matter development in formula fed infants and breast fed infants. Thirty-six infants (thirty breast fed and six formula fed) were scanned at 1 month and twenty-two (twelve breast fed and ten formula fed) at 3 months. Increased FA and decreased RD values were observed in breast fed infants at 1 month with differences becoming insignificant at 3 months.

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