In this study we combined rs-fMRI and diffusion MRI to assess the therapeutic capacity of cortically injected human neural stem cells in the mouse brain after stroke during 3 months. Seed-based analysis of diffusion anisotropy maps and functional connectivity were conducted interrelated with the main focus on the effect of stroke and treatment on the contralesional hemisphere. A delayed breakdown in functional network strength for the therapeutically treated group compared to a sham treated group is observed. However, diffusion anisotropy parameters stay stable with an increasing trend for the thalamus.
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