Abstract #2112

Quantifying Fibroglandular Tissue Volume using Chemical-Shift Encoded MRI: Validation in a Phantom

Leah C Henze Bancroft¹, Diego Hernando^1,2, Xiaoke Wang¹, Scott B Reeder^1,2,3,4,5, and Roberta M Strigel^1,2,6

¹Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁶Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, United States

Increased breast density is a known risk factor for the development of breast cancer. Quantitative MRI methods have the potential to provide accurate, volumetric measures of breast tissue volume and density. A novel, confounder-corrected chemical shift encoded (CSE) MRI technique designed to provide accurate fibroglandular tissue volume and density quantification is validated using a fat and water phantom. The CSE MRI technique provided accurate quantification of water and volumes and was robust to changes in spatial resolution and complexity of fat/water interfaces, indicating this method is expected to produce accurate and robust quantification of fibroglandular and adipose tissue in-vivo.

This abstract and the presentation materials are available to members only; a login is required.

Join Here