Changes in fat distribution and composition during ketonic diet were investigated in a sub group of twelve volunteers of a larger study. Liver fat concentrations in the examined cohort turned out to be surprisingly low compared to patient cohorts with similar BMI measured in other studies. The hypotheses that intra-hepatic fat may be reduced during a ketogenic diet could not be confirmed. However the composition of the sub group may have biased the outcome. While the MRI protocol and analysis worked well, MRS analysis of data acquired with the given protocol in subjects with low hepatic fat reaches its limitations.
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