We evaluated the feasibility of magnetic resonance elastography (MRE) for uterine fibroids and the effect of imaging sequences (i.e., spin-echo echo-planar imaging [SE-EPI] and gradient-echo [GRE]) on stiffness measurements. All MRE were performed in two cross-sectional planes (i.e., axial and sagittal). SE-EPI-MRE showed lower fibroid stiffness values than GRE-MRE. Each MRE method is a valid and reliable technique for measuring the stiffness of uterine fibroids.
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