Abstract #1896

Feasibility and value of VTE-ASL in quantitative evaluation of unilateral renal embolism in rabbits

Hanjing Kong¹, Fei Gao², Chengyan Wang¹, Yan Jia³, Hui Xu³, Xiaodong Zhang⁴, Li Yang³, Jue Zhang^1,2, Xiaoying Wang^1,4, and Jing Fang^1,2

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, ²College of Engineering, Peking University, Beijing, People's Republic of China, ³Renal Division, Peking University First Hospital, Beijing, People's Republic of China, ⁴Department of Radiology, Peking University First Hospital, Beijing, People's Republic of China

Arterial spin labeling with variable echo time (VTE-ASL) is a perfusion imaging technique capable of noninvasive estimating of GFR. But the application of VTE-ASL in renal disease is still lagging behind. The goal of this study was to investigate the feasibility of GFR and RBF using VTE-ASL in evaluation of unilateral renal embolism in rabbits. Compared with normal kidney, embolism area has large decrease in GFR and RBF, and was confirmed by histological findings.

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