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Abstract #1828

Prediction of Radiotherapy Response in Nasopharyngeal Carcinoma Patients Using Diffusion-Kurtosis Imaging

Weiyuan Huang1, Jiianjun Li2, Feng Chen3, Yingman Zhao4, and Xiaolei Zhu5

1Department of Radiology, Hainan General Hospital, Haikou, People's Republic of China, 2Department of Radiology, Hainan General Hospital, People's Republic of China, 3Department of Radiology, Hainan General Hospital, Haikou, China, People's Republic of China, 4department of Radiology, Hainan General Hospital, People's Republic of China, 5MR scientific marketing NE Asia, Siemens Healthcare

The first row: A 62-year-old man with NPC who was a nonresponder. The lesions located at the left nasopharyngeal wall and cavum. Manual draw an ROI within the boundaries of the NPC on Kmean map. The tumor’s maximum diameter was 3.5 before radiotherapy. Residual tumor was detected after radiotherapy. Mean Dmean and Kmean values were 1.48 10-3 mm2/s and 0.72 before treatment. The second row: A 63–year-old man with NPC who was a responder. The lesion affect the bilateral mucous membrane of the nasopharynx. The tumor’s maximum diameter was 3.09 before radiotherapy. No residual tumor was detected after radiotherapy. Mean Dmean and Kmean values were 1.22 10-3 mm2/s and 0.83 before treatment. NRG: non response group RG: reponse group

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Abstract