Abstract #1783

Solving the free water elimination estimation problem by incorporating T2 relaxation properties

Quinten Collier¹, Jelle Veraart^1,2, Arnold J. den Dekker^1,3, Floris Vanhevel⁴, Paul M. Parizel⁴, and Jan Sijbers¹

¹Vision Lab, University of Antwerp, Antwerp, Belgium, ²Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ³Delft Center for Systems and Control, Delft University of Technology, Delft, Netherlands, ⁴Department of Radiology, Antwerp University Hospital, Antwerp, Belgium

The free water elimination (FWE) model fitting problem is inherently ill-conditioned, leading to the need for solutions that can avoid or deal with these kinds of fitting problems. In this work, we evaluate a model extension to the FWE model that exploits the T2-relaxation properties and subsequently leads to a well-posed fitting problem that can be easily solved using standard estimation techniques.

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