Compared to monoexponential DWI model, biexponential and stretched exponential DWI models are feasible and useful in the noninvasive tissue characterization of renal tumors. Water molecular diffusion heterogeneity index (α) and Dt may provide additional information and could lead to improved differentiation with better sensitivity and specificity in differencing MFAML from ccRCC compared with mean ADC, Dp, fp, and DDC values in clinical setting.
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