In order to explore biomarkers to reflect the effects of long-term physical exercise (PE) on the activities in RSNs, the relationship among the history of participation in PE clubs, the activations in RSNs and the physical activity (PA) was investigated. The activation in the ACG was decreased depending on longer history of PE as well as higher PA indicated by IPAQ scales. These findings may reflect less demand for cognitive integration. It was suggested that both recovery and sedation of the activity in the RSNs against the age-related changes in brain activation may be the biomarker in healthy older adults.
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