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Abstract #1611

Chemical Shift T1 Quantification with Three-dimensional Ultrashort Echo Time Cones Imaging and IDEAL (3D UTE-Cones-IDEAL) Processing

Xing Lu1,2, Michael Carl3, Yajun Ma1, Yanchun Zhu1, Yinghua Zhao1, Wenhui Yang2, Eric Y Chang1,4, and Jiang Du1

1Department of Radiology, University of California, San Diego, CA, United States, 2Institute of Electrical Engineering, Chinese Academy of Science, Beijing, People's Republic of China, 3GE Healthcare, San Diego, CA, United States, 4Radiology Service, VA San Diego Healthcare System, San Diego, CA, United States

Conventional T1 measurements are subject to errors due to fat contamination and invisibility of the short T2 components. In this study, we aimed to develop 3D UTE with Cones sampling and IDEAL processing (3D UTE-Cones-IDEAL) with variable TRs for robust fat/water separation and more accurate T1 estimation of joint tissues ex vivo and in vivo. The results show that this technique can robustly separate water and fat signal and lead to longer T1s for water-rich tissues (such as muscle, tendon and peripheral nerve), and shorter T1s for fat-rich tissues.

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