Fast Bloch-Torrey simulation of 3D RF spoiled gradient echo sequences using a number of subvoxels and molecular diffusion effect

RF spoiled gradient echo sequences were studied both with experiments and Bloch-Torrey simulation. The Bloch simulation of the 256×256×32 voxel images clarified that adequate number of subvoxels were required for artifact-free images. The Bloch-Torrey simulation for one voxel magnetization clarified that adequate number of subvoxels were required for image intensity reproduction by diffusion effect. In conclusion, molecular diffusion effects are indispensable to reproduce the image contrast in SPGR.