MRE outcomes depend on various factors, which include SNR, spatial resolution, mechanical frequency, induced shear wave amplitude, and reconstruction method. It was formerly shown in a simulation study that 7 to 10 voxels were needed to properly resolve the shear wavelength, λref, and both accurately and precisely quantify the mechanical properties of the targeted tissue by inversion of the equation of motion. The purpose here is to experimentally reproduce the conditions defined by the simulation to determine the actual influence of the acquisition voxel size, a, on MRE acquisitions and validate the predicted λref/a conditions for optimal MRE reconstruction.
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