Abstract #1358

Proton Density Mapping and Receiver Bias Correction for Absolute Quantification with MR Fingerprinting

Anagha Deshmane¹, Debra McGivney², Yun Jiang¹, Dan Ma², and Mark Griswold²

¹Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Radiology, Case Western Reserve University, Cleveland, OH, United States

MR Fingerprinting (MRF) can simultaneously map multiple parameters and can be used to compute estimates of tissue fractions. However, MRF-derived M₀ maps contain information about both proton density (PD) and the receiver sensitivity profile (RP). Here we estimate relative PD and RP from MRF M₀ and T₁ maps. Relative PD and tissue fractions are combined for absolute quantity mapping of CSF, gray matter, and white matter as a fraction of the voxel equilibrium magnetization.

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