Abstract #1178

A Combined Intravascular MRI Endoscope and Intravascular Ultrasound (IVUS) Transducer for High-Resolution Image-Guided Ablation

Xiaoyang Liu^1,2, Nicholas Ellens¹, Emery Williams³, Everette Clif Burdette³, Parag Karmarkar¹, and Paul Bottomley^1,2

¹Russell H. Morgan Department of Radiology, Johns Hopkins University, Baltimore, MD, United States, ²Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States, ³Acoustic MedSystems, Inc, Champaign, IL, United States

An intravascular MRI (IMRI) loopless antenna is combined for the first time with an intravascular water-cooled ultrasound ablation transducer as a possible tool for providing high-resolution MRI-guided ablations of pathological tissue via intravascular access. High resolution anatomical MRI, and real-time MRI thermometry were used to monitor ablation delivery in phantoms and tissue specimens. Results show that IMRI can guide IVUS-mediated directional ablation with minimal image artifacts. This permits the monitoring of thermal dose and therapy titration while minimizing potential thermal damage to the vessel wall.

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