Vasculature plays an important role in white and brown adipose tissue (WAT and BAT) metabolism. In expanding WAT, abnormal vasculature may lead to energy (fat) deposition whereas in activated BAT it may potentially facilitate the energy consumption by oxidizing the fat. Understanding the vascular network and blood perfusion properties of the activated BAT is important for triglyceride clearance, increased blood flow and oxygen. In this feasibility study we have investigated the vascular properties and blood perfusion rate constant of the activated BAT by quantitative dynamic contrast enhanced MR imaging in a rodent model.
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