Abstract #0938

Off-Resonance Correction for MR Fingerprinting Using Multiple Frequency Interpolation

Jason Ostenson^1,2, Ryan K. Robison³, Nicholas R. Zwart³, and E. Brian Welch^1,4,5

¹Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States, ²Program in Chemical and Physical Biology, Vanderbilt University, Nashville, TN, United States, ³Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, United States, ⁴Department of Radiology and Radiological Sciences, Vanderbilt University, ⁵Department of Biomedical Engineering, Vanderbilt University

While T1 and T2 parameter mapping using fast imaging with steady-state precession (FISP) magnetic resonance fingerprinting (MRF) has shown consistency with classic relaxometry techniques under static field (B0) inhomogeneity, the use of spiral k-space trajectories blurs parameter map boundaries in regions of high B0 variability. This work shows deblurring in phantom and in vivo relaxation maps generated using a published MRF sequence in conjunction with multi-frequency interpolation (MFI) acquired using undersampled and fully sampled spirals on a 3 Tesla human MR scanner.

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