Abstract #0537

Detection of Internal Tissue Disruptions within the Intervertebral Disc via Magnetic Resonance Elastography: A Feasibility Study

Benjamin A Walter^1,2, Prasath Mageswaran^1,3, Elizabeth Yu^1,4, Safdar Khan^1,4, William S Marras^1,3, and Arunark Kolipaka^1,5

¹Spine Research Institute, The Ohio State University, Columbus, OH, United States, ²Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, ³Department of Integrated Systems Engineering, The Ohio State University, Columbus, OH, United States, ⁴Department of Orthopaedics, The Ohio State University Wexner Medical Center, Columbus, OH, United States, ⁵Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States

Magnetic resonance elastography (MRE) was used to non-invasively assess regions of internal tissue disruption within intervertebral discs (IVD) that were known to contain tissue damage. Internal tissue disruptions were assessed via measurements of wave continuity as they propagated throughout the IVD. Results demonstrated that injured IVD’s had an elevated octahedral shear strain (OSS) compared to non-operated control IVDs and OSS maps allowed visualization of potential location of internal tissue disruptions. Overall, results of this study suggest that MRE may provide a non-invasive way of identifying internal tissue disruptions within the IVD.

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