Comparable intrinsic spatial profiles of BOLD signals and local field potentials after stimulation and in resting-state within primary somatosensory cortex

We directly compared the spatial extents of stimulated activations and the profiles of inter-voxel resting-state correlations between high resolution BOLD data at 9.4T and local field potentials (LFPs) using 98-channel microelectrode arrays, in functionally distinct somatosensory areas 3b and 1 in monkeys. We found the point spread functions of BOLD and LFP responses were comparable (~1mm) in the stimulus condition, and were more spatially constrained than correlations at rest. Our results showed spatial agreement of resting-state functional connectivity between BOLD and LFP and demonstrated that BOLD responses were as focal as underlying electrical activity.