Abstract #0431

Longitudinal Characterization of Liver Regeneration and Portal Hemodynamics in Living Donor Liver Transplant

Alejandro Roldán-Alzate^1,2,3, David R Rutkowski², Luis A Fernandez⁴, and Scott B Reeder^1,3,5,6

¹Radiology, University of Wisconsin, Madison, WI, United States, ²Mechanical Engineering, University of Wisconsin, Madison, WI, United States, ³Biomedical Engineering, University of Wisconsin, Madison, WI, United States, ⁴Surgery, University of Wisconsin, Madison, WI, United States, ⁵Medical Physics, University of Wisconsin, Madison, United States, ⁶Medicine, University of Wisconsin, Madison, United States

The purpose of this study was to evaluate longitudinal liver regeneration and hemodynamic changes of living donor liver transplant (LDLT) donors in response to surgical liver resection. Five living related liver donors were studied. Subjects were imaged using 4D Flow MRI before and at several times following partial hepatectomy. The ability to longitudinally evaluate liver regeneration and portal hemodynamic changes non-invasively demonstrates that 4D flow MRI is a suitable tool for both surgical planning of LDLT, and for improved understanding of the liver regeneration and hemodynamic changes that occur in the remnant liver of the donor.

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