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Abstract #0358

Whole-Brain Arteriography and Venography Using an Improved Velocity-Selective Saturation (VSS) Pulse Trains

Wenbo Li1,2, Feng Xu 1,2,3, Jing Liu1,4, Michael Schär1, Taehoon Shin5, Peter van Zijl1,2, Ye Qiao1, Bruce Wasserman1, and Qin Qin1,2

1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, 3Developing Brain Research Lab, Children’s National Medical Center, Washington, DC, United States, 4Department of Radiology, People’s Hospital, Guangzhou, People's Republic of China, 5Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, MD, United States

Velocity-selective (VS) MRA, a non-subtractive technique and allows large spatial coverage and slow-flow depiction has shown recent promise for cerebral applications at 3T. Here, we improved the velocity-selective saturation (VSS) pulse train by reducing its sensitivity of tissue suppression to B1 inhomogeneity for both the intracranial and cervical regions. Moreover, we propose that arteriograms or venograms can be obtained by placing spatially selective inversion pulses before the acquisition to selectively null signals from venous or arterial blood. The feasibility of these technical advances for VS MRA is demonstrated on healthy volunteers at 3T.

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