Presence of motion during MRSI acquisition and scanner instabilities affect the localization accuracy of the measurement and consequential quality of the data. We determined the extent of inter-acquisition head movement, frequency and B0 shim changes during approximately 20 min MEGA-edited MRSI scan with integrated vNav in 4 different groups of subject, with significantly larger amount of head motion in Parkinsons's patients, Mild Cognitive Impairment and elderly controls comparing to young healthy volunteers. With real-time motion, B0 correction and reacquisition we obtained satisfactory data quality in all groups of subjects, which makes it a valuable tool for spectral quality accurance.
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