Our meta-analysis indicates that patients with T2DM have significantly and robustly reduced grey matter, mainly in the cortical-striatal-limbic networks. The meta-regression results suggest that T2DM patients with longer illness duration may have smaller grey matter volume in the right MTG. Our finding supports the notion that T2DM could lead to subtle diabetic brain structural changes, which may be correlated with cognitive impairment inT2DM patients.
This abstract and the presentation materials are available to members only; a login is required.