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Abstract #0021

3D magnetic resonance spectroscopic imaging at 7 Tesla of patients with medically refractory focal epilepsy with non-lesional or inconclusive clinical MRIs: First Results

Rebecca Emily Feldman1, Madeline Cara Fields2, Bradley Neil Delman3, Lara Vanessa Marcuse4, and Priti Balchandani1

1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Department of Neurology, Mount Sinai Hospital, New York, NY, United States, 3Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 4Department of Neurology, Mount Sinai Hospital

SASSI is a B1-insensitive, low-SAR 7T MRSI technique with reduced chemical shift localization errors. We used 3D SASSI to image the hippocampi of patients with medically refractory focal epilepsy who had non-lesional or inconclusive clinical MRIs. Using SASSI at 7T, we detected decreases in the hippocampal NAA/Cr ratios in suspected temporal lobe epilepsy patients, on the same side as the seizure onset zones and/or 7T structural findings.

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