Abstract #4455
Geometrical complexity of left ventricular endocardial border measured by fractal analysis: a comprehensive study
Andrea S. Dell'Aquila 1 , Sofia A. Papadopoulou 1 , Sanjay Sharma 1 , Lisa J. Anderson 1 , and Taigang He 1
1
Cardiovascular Sciences Research Centre, St
George's, University of London, London, Greater London,
United Kingdom
Increased left ventricle trabeculations (LVT) are
frequently seen in various cardiac diseases. LVT can be
accurately delineated from cardiovascular magnetic
resonance (CMR) images, but methods to quantify them
remain limited. Fractal analysis of CMR images was
recently proposed and proved to be an effective
quantitative measure in distinguishing normal from
hypertrophic cardiomyopathy. In this study, we
quantified LVT using fractal dimension in a large cohort
of normal controls, athletes with and without athlete
heart syndrome, patients with non-compaction,
hypertrophic and non-ischaemic dilated cardiomyopathy.
Of clinical importance, this study demonstrates a wide
spectrum of LVT patterns between normal cardiac
conditions and abnormal ones, such as hypertensive heart
disease, hypertrophic cardiomyopathy and left
ventricular non-compaction.
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