Abstract #4444
Optimization of Spinal Cord NODDI Protocol with Multi-band EPI for Clinical Use
Masaaki Hori 1,2 , Ryuji Nojiri 2 , Katsutoshi Murata 3 , Yuichi Suzuki 4 , Koji Kamagata 1 , Mariko Yoshida 1 , Kouhei Tsuruta 1,5 , Keiichi Ishigame 2 , and Shigeki Aoki 1
1
Radiology, Juntendo University School of
Medicine, Tokyo, Japan,
2
Tokyo
Medical Clinic, Tokyo, Japan,
3
Siemens
Japan K.K., Tokyo, Japan,
4
Radiology,
The University of Tokyo Hospital, Tokyo, Japan,
5
Department
of Health Science, Graduate School of Human Health
Sciences, Tokyo Metropolitan University, Tokyo, Japan
We investigate the effect of multi-band reduction factor
(MBf) on Neurite orientation dispersion and density
imaging (NODDI) metrics and to compare less number of
motion probing gradient (MPG) axes 2-shell protocol
NODDI metrics with 2-shell 30 MPG protocol in the
cervical spinal cord white matter in vivo. Between Mbf 2
and 3 data, there were significant differences in ICVF
and IVF. With increasing of number of measurements,
improved agreement was observed between 30 MPG data
metrics and less number MPG data. Therefore, we
recommend that more than 24 MPG axes and MBf of 2 for
spinal cord NODDI with multiband-EPI.
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