Abstract #4442
Investigating functional-structural correlations in the cervical spinal cord in vivo
Moreno Pasin 1 , Marios C Yiannakas 1 , Ahmed T Toosy 2 , and Claudia A M Wheeler-Kingshott 1
1
NMR Research Unit, Department of
Neuroinflammation, Queen Square MS Centre, UCL
Institute of Neurology, London, England, United Kingdom,
2
Department
of Brain Repair and Rehabilitation, UCL Institute of
Neurology, London, England, United Kingdom
Investigating spinal cord function and white matter
microstructure using MRI implies coping with several
technical issues. This study uses a protocol matching
functional and structural spinal images and investigates
correlations between functional and structural
parameters obtained in 10 healthy controls undertaking a
sensory task delivered on both left and right hand
separately. Signal enhancement and lateralization
index(LI) are reported. Fractional anisotropy(FA),
radial diffusivity(RD), axial diffusivity(AD) and mean
diffusivity(MD) were calculated in ROIs drawn on: whole
cord, right hemisphere, left hemisphere and posterior
column white matter. No correlation was found between LI
and the FA, MD, RD and AD values for any ROIs.
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