Abstract #4391
Peritumoral Myelin Imaging In Low-Grade Astrocytomas
Hagen H Kitzler 1 , Hannes Wahl 1 , Tareq Yuratli 2 , and Matthias Meinhardt 3
1
Neuroradiology, Technische Universitaet
Dresden, Dresden, SN, Germany,
2
Neurosurgery,
Technische Universitaet Dresden, Dresden, SN, Germany,
3
Neuropathology,
Technische Universitaet Dresden, Dresden, SN, Germany
We used the whole-brain relaxation method
Multi-component Driven Equilibrium Single Pulse
Observation of T1 and T2 (mcDESPOT) to retrieve
myelination information in astrocytic low-grade brain
tumors and their adjacent peritumoral tissue. Little is
known about the peritumoral white matter change although
specific tissue changes altering the peritumoral tissue
composition may precede the invasion. This feasibility
study demonstrates subtle peritumoral myelin loss
measurable with myelin imaging.
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