Abstract #4389
Multiparametric MRI Towards a Predictive Model to Differentiate Solitary Brain Metastasis from Glioblastoma Multiforme
Kambiz Nael 1 and Adam H Bauer 1
1
Medical Imaging, University of Arizona,
Tucson, AZ, United States
Solitary brain metastasis and glioblastoma multiforme
(can appear similar on conventional MRI and therefore
reliable imaging differentiation between MET and GBM is
important for medical staging, surgical planning, and
therapeutic decision making. In this study we propose
and show the advantage of multiparametric MR biomarkers
including fractional anisotropy and mean diffusivity
derived from DTI, relative cerebral blood volume derived
from DSC perfusion and microvascular permeability
(Ktrans) derived from dynamic contrast enhanced
perfusion towards a predictive model for differentiation
of solitary metastasis from GBM.
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